#1: Ketamine resets brain circuitry
Glutamate regulates large regions of the nervous systems and is the most prominent neurotransmitter in ihe brain. When glutamate receptors are over-activated, as in cases of major depressive disorder (MOD) and post-traumatic stress disorder (PTSD), a person may experience depression and anxiety. Ketamine works by blocking glutamine receptors in the brain. Some studies sugge1 PTSD may stem from a lack of synaptic connectivity. Ketamine therapy works by enhancing synaptic connectivity in brain circuitry, which may provide relief from PTSD symptoms.

#2: Ketamine may be able to reverse tire effects of stress
Because glutamate synapses play a critical role in the brain, it is possible that the use of ketamine may enhance synaptic connectivity in brain circuits, uhimately relieving, and even reversing, the effects of strcSs.

#3 Ketamine is an effective PTS(D} treatment because it works quickly and may work w/ren ot/rer treatments /rave failed
Ketamine may work especially well among patients who are resistant to other forms of treatment like anti-depressants and cognitive therapy. According to the National Center of Biotechnical Information, Ketamine is gaining popularity in treating major depressive disorder (MOD) that has previously been treatment-resistant.

How Ketamlne is Administered
During the treatment, the initial infusions usually take place over approximately two weeks with six infusions that are administered every other day.
Io pans of the brain that control mood and emotions, ketamine infusion creates new connections in the brain. These new neurological connectfons help the brain to send positive signals to the psyche, along with beneficial physical conditions to the body. The effect is notable within hours, but most patients repon the results are instantaneous. These astonishing changes can be seen on brain scans and imaging. And the results are long-lasting.

Ketamine impacts both mood and anxiety and can result i11 positive treatment outcomes for the following disorders:

• Severe or Chronic Depression
• Bipolar Disorder
• Obsessive Compulsive Disorder (OCD)
• Post-Partum Depression {PPD)
• Post-Traumatic Stress Disorder {PTSD)
• Produces Rapid Onset of Neural Connections

Dr. Stephen Reichbach states, “ln our opinion, TV Ketantine infusions are the gold standard patients with severe mood disorders. rv ketamine provides 100% bioavailability meaning that I 00% of the drug administered, gels where it needs to go (the brain). This provides easier titration and a higher likelihood for a positive response. At the end of the day, the out of pocket cost t0 the patient may be more than the TV infusions depending on an individual’s insurance coverage, not to mention the time convenience advantage for the patient of the N ketamine infusions.”

Stephen Reichbach, MD, Board-Certified Anesthesiologist, specializes in pain management. For more information, please contact their office today at 941-213-4444, or visit their website at findpainrelief.com.

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